University of Virginia, Charlottesville, USA
Bradford (Brad) B. Worrall, MD, MSc, is a Professor and Vice-Chair for Clinical Research of Neurology and Professor of public health sciences at the University of Virginia where he directs the Vascular Neurology Fellowship. He is the Deputy Editor of the journal neurology for which he handles the cerebrovascular disease and critical care portfolio.
He has been active in numerous clincal trials dedicated to stroke's genetic factors over the past two decades, including the Ischaemic Stroke Genetics Study (ISGS); the Siblings with Ischaemic Stroke Study (SWISS); the Genetics of Intracerebral Hemorrhage in Anticoagulation (GOCHA) study; the Familial Intracranial Aneurysm (FIA) study; and Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH).
He has also co-PI'd a U-01 funded GWAS of treatement response grant with Michele Sale using the Vitamin Intervention for Stroke Prevention (VISP) trial. The overall project is known as the Genome-wide Association Research Network into Effects of Treatment (GARNET) and included a wide range of randomised clinical trials in many disease types. He co-PI'd the NINDS Stroke Genetics Network (SiGN) study funded by the NIH/NINDS, co-chaired the phenotype harmonization committees for both grants, and chaired the Incidental Findings and Return of Results Committee for GARNET.
He currently benefits from a reserach grant allowing for the investigation of reciprocal screening for aneurysmal disease and the creation of a biobank (the Brain and Aortic Aneurysm Screening (BAAS) study). He is co-PI on the Stroke Central Atlantic Network for Research (SCANR) site in the NIH/NINDS funded StrokeNet program (consortium of 25 selected programs across the United States to conduct clinical and translational research in strokes, focused on prevention, acute treatment and recovery.
Dr. Worrall is a founding member of the International Stroke Genetics Consortium and currently serves on the Executive committee. He previously served as chair of the METASTROKE consortium within the ISGC. He runs a translational stroke genetics laboratory at the University of Virginia and has a pilot study looking at the gut microbiome and stroke recovery. Dr. Worrall recently served as Fulbright Distinguished Chair for Research at the Hunter Medical Research Institute and University of Newcastle in Australia.